3'-Deoxycytidine(CAS: 7057-33-2)

3'-Deoxycytidine (CAS: 7057-33-2) is a white or off-white crystalline compound with a molecular weight of approximately 232.22 g/mol. It is slightly soluble in water and ethanol. The compound is relatively stable under normal conditions but can be susceptible to hydrolysis under acidic or basic conditions. It is also reactive towards nucleophilic substitution at the 3'-position.

3'-Deoxycytidine is typically synthesized via nucleobase modification of cytidine. A common method involves the use of a deoxycytidine-5'-monophosphate derivative as a starting material. The synthesis often employs catalytic amounts of a suitable base, such as sodium hydride, to facilitate the deoxygenation at the 3'-position. The yield and selectivity can be optimized through careful control of reaction conditions.

3'-Deoxycytidine (CAS: 7057-33-2) finds applications in pharmaceuticals, particularly in the development of antiviral drugs. It is also utilized in the synthesis of nucleoside analogs for polymerase chain reaction (PCR) applications and in the production of certain types of sensors and semiconductors.

Proper handling of 3'-Deoxycytidine (CAS: 7057-33-2) requires the use of personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a cool, dry place away from heat sources and incompatible materials. If a spill occurs, it should be immediately cleaned up under a fume hood. Always refer to the safety data sheet (SDS) for specific handling instructions and emergency procedures.