Compound Q&A

How is (2E)-3-(2,3,4-Trifluorophenyl)acrylic acid (CAS: 207742-85-6) typically synthesized?

Answer

(2E)-3-(2,3,4-Trifluorophenyl)acrylic acid
(2E)-3-(2,3,4-Trifluorophenyl)acrylic acid is typically synthesized via a Friedel–Crafts alkylation reaction of 2,3,4-trifluorophenylacetylene with acrylic acid. This process involves the use of a Lewis acid catalyst and requires careful control of temperature and pressure to achieve high yield and selectivity.

About

English Name (2E)-3-(2,3,4-Trifluorophenyl)acrylic acid
Molecular Formula C9H5F3O2
Molecular Weight 202.13 g/mol
SMILES C1=CC(=C(C(=C1C=CC(=O)O)F)F)F
InChIKey AYDLBRHSHLRVAH-DUXPYHPUSA-N
Last Updated: 2025-10-28 15:15

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