Compound Q&A
How is tert-Butyl (1-acetylpiperidin-4-yl)carbamate (CAS: 283167-28-2) typically synthesized?
Answer
tert-Butyl (1-acetylpiperidin-4-yl)carbamate is typically synthesized by the reaction of tert-butyl piperidin-4-ylcarbamate with acetic anhydride in the presence of a catalytic amount of a base such as pyridine. The reaction is carried out at room temperature, and the product is isolated by column chromatography. This method provides a yield of around 85%.
About
CAS No
283167-28-2
English Name
tert-Butyl (1-acetylpiperidin-4-yl)carbamate
Molecular Formula
C12H22N2O3
Molecular Weight
242.32 g/mol
SMILES
CC(=O)N1CCC(CC1)NC(=O)OC(C)(C)C
InChIKey
YBNZMQXSIQUIHZ-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54
