Compound Q&A

What are the main uses of Evolocumab (CAS: 1256937-27-5)?

Answer

Evolocumab
Evolocumab (CAS: 1256937-27-5) is primarily used to lower low-density lipoprotein (LDL) cholesterol in patients with hypercholesterolemia and heterozygous familial hypercholesterolemia. It is especially beneficial for those who do not achieve adequate cholesterol levels with statins or who cannot tolerate statins.

About

English Name Evolocumab
Molecular Formula C58H97N15O16S2Se
Molecular Weight 1403.6 g/mol
SMILES C[C@@H]1CC=N[C@H]1C(=NCCCC[C@@H](C(=O)C(=O)[C@H](CS)NN[C@@H](C[SeH])C(=O)C(=O)[C@H](CCSC)N=C([C@H](C)NN[C@@H](CC(=N)O)C(=O)O)O)N=C([C@H](CC(C)C)N=C([C@H](CCCCN=C([C@H]2[C@@H](CC=N2)C)O)N=C([C@H](C(C)C)N=C([C@H](CCC(=O)O)N)O)O)O)O)O
InChIKey HSSNUIIWBIUJJV-WKJVYGORSA-N
Last Updated: 2025-10-27 23:53

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