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Evolocumab(CAS: 1256937-27-5)
CAS Number
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Basic Information
Molecular Formula
C58H97N15O16S2Se
Molecular Weight
1403.6 g/mol
Chemical Identifiers
SMILES
C[C@@H]1CC=N[C@H]1C(=NCCCC[C@@H](C(=O)C(=O)[C@H](CS)NN[C@@H](C[SeH])C(=O)C(=O)[C@H](CCSC)N=C([C@H](C)NN[C@@H](CC(=N)O)C(=O)O)O)N=C([C@H](CC(C)C)N=C([C@H](CCCCN=C([C@H]2[C@@H](CC=N2)C)O)N=C([C@H](C(C)C)N=C([C@H](CCC(=O)O)N)O)O)O)O)O
InChIKey
HSSNUIIWBIUJJV-WKJVYGORSA-N
Database References
FAQ
Evolocumab (CAS: 1256937-27-5) is a monoclonal antibody used in the treatment of hypercholesterolemia and heterozygous familial hypercholesterolemia. It is administered subcutaneously and works by inhibiting proprotein convertase subtilisin/kexin type 9 (PCSK9), which reduces low-density lipoprotein (LDL) cholesterol levels.
Evolocumab (CAS: 1256937-27-5) is primarily used to lower low-density lipoprotein (LDL) cholesterol in patients with hypercholesterolemia and heterozygous familial hypercholesterolemia. It is especially beneficial for those who do not achieve adequate cholesterol levels with statins or who cannot tolerate statins.
Evolocumab (CAS: 1256937-27-5) is generally considered safe. However, like all medications, it may cause side effects such as injection site reactions, headache, and injection-related itching. Precautions should be taken to avoid hypersensitivity reactions and to monitor patients for any adverse effects.
Evolocumab (CAS: 1256937-27-5) should be stored refrigerated at 2 to 8°C (36 to 46°F) and should not be frozen. It should be protected from light and kept in its original package to maintain its stability. Unused vials should be discarded if they are not used within 28 days after first use.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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