Compound Q&A
How is 3-Fluoro-2-(trifluoromethyl)benzoic acid (CAS: 261951-80-8) typically synthesized?
Answer
3-Fluoro-2-(trifluoromethyl)benzoic acid is typically synthesized via the Friedel-Crafts alkylation of 2-(trifluoromethyl)benzoic acid with fluorobenzene in the presence of aluminum chloride as a catalyst. The reaction yields a mixture, but selective methods can be used to improve product purity.
About
CAS No
261951-80-8
English Name
3-Fluoro-2-(trifluoromethyl)benzoic acid
Molecular Formula
C8H4F4O2
Molecular Weight
208.11 g/mol
SMILES
OC(=O)c1cccc(F)c1C(F)(F)F
InChIKey
CDGGKKODENBDJO-UHFFFAOYSA-N
Last Updated: 2025-10-26 09:39
