Compound Q&A
How is 7-Methoxy-1H-indole-3-carboxylic acid (CAS: 128717-77-1) typically synthesized?
Answer
7-Methoxy-1H-indole-3-carboxylic acid can be synthesized via the condensation of 7-methoxyindole with trichloroacetyl chloride in the presence of a catalyst like 4-Acetamidobenzene or 4-acetamidobenzoyl chloride. The reaction yields a mixture of isomers, with the desired product being separated by column chromatography.
About
CAS No
128717-77-1
English Name
7-Methoxy-1H-indole-3-carboxylic acid
Molecular Formula
C10H9NO3
Molecular Weight
191.19 g/mol
SMILES
COC1=CC=CC2=C1NC=C2C(=O)O
InChIKey
MSALXMDIYCKASR-UHFFFAOYSA-N
Last Updated: 2025-10-26 09:38
