Compound Q&A
How are Lamotrigine EP Impurity B and Lamotrigine EP Impurity C (CAS: 84689-20-3) typically synthesized?
Answer
Lamotrigine EP Impurity B and C are typically synthesized as by-products during the production of lamotrigine. Common synthetic methods include alkylation and reduction steps, often using reagents like propionyl chloride and sodium borohydride. The synthesis involves catalytic hydrogenation and alkyl halide substitution reactions. The purity and selectivity of these impurities can vary depending on the process conditions and the quality of starting materials.
About
CAS No
84689-20-3
English Name
Lamotrigine EP Impurity B and Lamotrigine EP Impurity C
Molecular Formula
C9H7Cl2N5
Molecular Weight
256.09 g/mol
SMILES
NC(=N)NN=C(c1cccc(c1Cl)Cl)C#N
InChIKey
MLWONQDCGJOILV-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31
