Compound Q&A
How is 2-Chloro-4-nitro-1-(trifluoromethyl)benzene (CAS: 151504-80-2) typically synthesized?
Answer
2-Chloro-4-nitro-1-(trifluoromethyl)benzene is typically synthesized via the nitration of 2-chloro-1-(trifluoromethyl)benzene followed by chlorination. Commonly, sulfuric acid and nitric acid are used as the nitrating mixture, while thionyl chloride is employed for chlorination. The reaction conditions must be carefully controlled to achieve high yield and selectivity.
About
CAS No
151504-80-2
English Name
2-Chloro-4-nitro-1-(trifluoromethyl)benzene
Molecular Formula
C7H3ClF3NO2
Molecular Weight
225.55 g/mol
SMILES
C1=CC(=C(C=C1[N+](=O)[O-])Cl)C(F)(F)F
InChIKey
MOTWHSMEZCFDOD-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31
