Compound Q&A
How is 2-Chloro-6-(trifluoromethoxy)-1,3-benzothiazole (CAS: 133840-96-7) typically synthesized?
Answer
2-Chloro-6-(trifluoromethoxy)-1,3-benzothiazole is typically synthesized via electrophilic aromatic substitution. The reaction involves the condensation of 2-chloro-3,5-difluorobenzoyl chloride with 1,3-benzothiazole in the presence of a catalyst like a Lewis acid. The reaction is carried out under anhydrous conditions to ensure high selectivity and yield.
About
CAS No
133840-96-7
English Name
2-Chloro-6-(trifluoromethoxy)-1,3-benzothiazole
Molecular Formula
C8H3ClF3NOS
Molecular Weight
253.63 g/mol
SMILES
FC(F)(F)Oc1ccc2nc(Cl)sc2c1
InChIKey
PPGSYGPSOLZOOU-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31
