Compound Q&A

How is 2-{[(2-Methyl-2-propanyl)oxy]carbonyl}-1-isoindolinecarboxylic acid (CAS: 221352-46-1) typically synthesized?

Answer

2-{[(2-Methyl-2-propanyl)oxy]carbonyl}-1-isoindolinecarboxylic acid
2-{[(2-Methyl-2-propanyl)oxy]carbonyl}-1-isoindolinecarboxylic acid can be synthesized via a multi-step process involving the protection of an alcohol followed by the formation of an ester. Common reagents include N,N-dimethylformamide (DMF) and 4-dimethylaminopyridine (DMAP) as a catalyst. The yield is typically around 70-80%, and the reaction is carried out under mild conditions to ensure high selectivity.

About

English Name 2-{[(2-Methyl-2-propanyl)oxy]carbonyl}-1-isoindolinecarboxylic acid
Molecular Formula C14H17NO4
Molecular Weight 263.29 g/mol
SMILES CC(C)(C)OC(=O)N1CC2=CC=CC=C2C1C(=O)O
InChIKey BBMCBMREDOQCDU-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24

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