Compound Q&A
How is Norgestimate (CAS: 35189-28-7) typically synthesized?
Answer
Norgestimate (CAS: 35189-28-7) is typically synthesized via a multi-step process starting from progesterone. The key steps include acetylation, oxidation, and reduction. The reaction involves the use of acetic anhydride for acetylation, followed by catalytic oxidation with chromic acid. The reduction step often uses sodium borohydride. The overall process yields Norgestimate with good selectivity, and the final product is purified by recrystallization and chromatography techniques.
About
CAS No
35189-28-7
English Name
Norgestimate
Molecular Formula
C23H31NO3
Molecular Weight
369.5 g/mol
SMILES
O/N=C/1\CC[C@H]2C(=C1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@]2(C#C)OC(=O)C)CC
InChIKey
KIQQMECNKUGGKA-NMYWJIRASA-N
Last Updated: 2025-10-22 19:24
