Compound Q&A

What are the physical and chemical properties of N-[(8S)-4-Amino-6-methyl-5-(3-quinolinyl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl]acrylamide (CAS: 1661854-97-2)?

Answer

N-[(8S)-4-Amino-6-methyl-5-(3-quinolinyl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl]acrylamide
The compound is a crystalline solid with a high molecular weight around 600 g/mol. It has good solubility in common organic solvents like DMSO and moderate solubility in water. Chemically, it is reactive towards nucleophiles and can undergo various transformations such as amidation and conjugate addition. It is stable under normal laboratory conditions but should be stored away from strong acids and bases.

About

English Name N-[(8S)-4-Amino-6-methyl-5-(3-quinolinyl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl]acrylamide
Molecular Formula C23H20N6O
Molecular Weight 396.45 g/mol
SMILES CC1=C[C@@H](Cn2c1c(c3c2ncnc3N)c4cc5ccccc5nc4)NC(=O)C=C
InChIKey MKCYPWYURWOKST-INIZCTEOSA-N
Last Updated: 2025-10-22 12:37

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