Compound Q&A

How is Ethyl 4,6-dichloro-1H-indole-2-carboxylate (CAS: 53995-82-7) typically synthesized?

Answer

Ethyl 4,6-dichloro-1H-indole-2-carboxylate
Ethyl 4,6-dichloro-1H-indole-2-carboxylate (CAS: 53995-82-7) is typically synthesized through a multi-step process involving the condensation of 4,6-dichloro-1H-indole with ethyl chloroformate in the presence of a base like potassium carbonate. The yield is generally good, and the reaction is carried out under mild conditions.

About

CAS No 53995-82-7
English Name Ethyl 4,6-dichloro-1H-indole-2-carboxylate
Molecular Formula C11H9Cl2NO2
Molecular Weight 258.1 g/mol
SMILES CCOC(=O)C1=CC2=C(N1)C=C(C=C2Cl)Cl
InChIKey YLAHLUPONQVSOT-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37

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