Compound Q&A

How is 4-Fluoro-2-methoxypyridine (CAS: 96530-81-3) typically synthesized?

Answer

4-Fluoro-2-methoxypyridine
4-Fluoro-2-methoxypyridine is typically synthesized through the reaction of 2-methoxypyridine with hydrofluoric acid. This process involves the introduction of a fluorine atom at the 4-position of the pyridine ring. The yield is generally around 75-80%, and the reaction is performed under anhydrous conditions to avoid hydrolysis.

About

CAS No 96530-81-3
English Name 4-Fluoro-2-methoxypyridine
Molecular Formula C6H6FNO
Molecular Weight 127.12 g/mol
SMILES COC1=NC=CC(=C1)F
InChIKey RGWFJFBUHTUVMV-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37

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