Compound Q&A

How is 3-Iodotetrahydrofuran (CAS: 121138-01-0) typically synthesized?

Answer

3-Iodotetrahydrofuran
3-Iodotetrahydrofuran can be synthesized by treating iodomethane with tetrahydrofuran (THF) in the presence of a catalytic amount of base, such as potassium hydroxide. The reaction is typically carried out in an aprotic solvent. The selectivity and yield are high, with the product isolated by simple distillation.

About

English Name 3-Iodotetrahydrofuran
Molecular Formula C4H7IO
Molecular Weight 198.00299999999996 g/mol
SMILES C1COCC1I
InChIKey BKIQORJIKOPRCG-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37

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