Compound Q&A

What is Neratinib Maleate (CAS: 915942-22-2)?

Answer

Neratinib Maleate
Neratinib Maleate is a potent irreversible tyrosine kinase inhibitor, primarily used in the treatment of HER2-positive metastatic breast cancer. It has the chemical formula C22H25N3O5.H2C2O4 and is known for its ability to inhibit multiple HER family members, including HER1, HER2, and HER4.

About

English Name Neratinib Maleate
Molecular Formula C34H36ClN5O7
Molecular Weight 662.14 g/mol
SMILES CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C.C(=CC(=O)O)C(=O)O
InChIKey ZLRINKRBPGHRLB-AJOUBPDISA-N
Last Updated: 2025-10-21 21:33

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