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Neratinib Maleate(CAS: 915942-22-2)
CAS Number
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![(2S)-Amino[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid](https://static.chemtradehub.com/structs/422/42228-92-2-8448.webp)
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Basic Information
Molecular Formula
C34H36ClN5O7
Molecular Weight
662.14 g/mol
Chemical Identifiers
SMILES
CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C.C(=CC(=O)O)C(=O)O
InChIKey
ZLRINKRBPGHRLB-AJOUBPDISA-N
Database References
MDL Number
MFCD20489458
FAQ
Neratinib Maleate is a potent irreversible tyrosine kinase inhibitor, primarily used in the treatment of HER2-positive metastatic breast cancer. It has the chemical formula C22H25N3O5.H2C2O4 and is known for its ability to inhibit multiple HER family members, including HER1, HER2, and HER4.
Neratinib Maleate is mainly used to treat HER2-positive metastatic breast cancer. It is also investigated for its potential in treating other types of cancers, such as colorectal cancer and gastric cancer, due to its broad spectrum of activity against HER family members.
Neratinib Maleate is generally considered safe when used as directed. However, it can cause side effects such as diarrhea, rash, and hyperglycemia. Patients should follow medical advice, regularly monitor health, and take necessary precautions to avoid adverse reactions.
Neratinib Maleate should be stored at room temperature (15-30°C) away from direct sunlight and moisture. It should be kept in a tightly sealed container to maintain its stability and efficacy. Avoid exposure to extreme temperatures or humidity, as this may affect its potency and safety.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
Contact Person
Jiang Kun
1273554466@qq.com