Compound Q&A
How is (5-methoxy-1H-indol-2-yl)-phenylmethanone (CAS: 74588-78-6) typically synthesized?
Answer
(5-methoxy-1H-indol-2-yl)-phenylmethanone (CAS: 74588-78-6) is typically synthesized by the condensation of 5-methoxyindole and benzyl chloromethyl ketone. The reaction is usually carried out in the presence of a base like triethylamine, and the product can be isolated by recrystallization. Selectivity and yield are controlled by reaction conditions and solvent choice.
About
CAS No
74588-78-6
English Name
(5-methoxy-1H-indol-2-yl)-phenylmethanone
Molecular Formula
C16H13NO2
Molecular Weight
251.29 g/mol
SMILES
COC1=CC2=C(C=C1)NC(=C2)C(=O)C3=CC=CC=C3
InChIKey
ICMIJSRDISNKOC-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
