(5-methoxy-1H-indol-2-yl)-phenylmethanone(CAS: 74588-78-6)

(5-methoxy-1H-indol-2-yl)-phenylmethanone (CAS: 74588-78-6) has a white crystalline form with a molecular weight of approximately 260.26 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is stable under normal conditions but reacts with strong acids and bases. It is a key intermediate in the synthesis of various indole derivatives used in pharmaceuticals and agrochemicals.

(5-methoxy-1H-indol-2-yl)-phenylmethanone (CAS: 74588-78-6) is typically synthesized by the condensation of 5-methoxyindole and benzyl chloromethyl ketone. The reaction is usually carried out in the presence of a base like triethylamine, and the product can be isolated by recrystallization. Selectivity and yield are controlled by reaction conditions and solvent choice.

(5-methoxy-1H-indol-2-yl)-phenylmethanone (CAS: 74588-78-6) is used in the pharmaceutical industry for the synthesis of novel drug candidates. It is also relevant in the agrochemical sector due to its potential as an intermediate in the development of herbicides and pesticides. It may also find application in the production of semiconductors and sensors.

When handling (5-methoxy-1H-indol-2-yl)-phenylmethanone (CAS: 74588-78-6), it is essential to use proper personal protective equipment (PPE) such as gloves and safety goggles. Store the compound in a fume hood due to its potential volatility. In case of a spill, use appropriate absorbents and dispose of them according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.