Compound Q&A

How is (2-Bromo-1,3-thiazol-5-yl)methanol (CAS: 687636-93-7) typically synthesized?

Answer

(2-Bromo-1,3-thiazol-5-yl)methanol
(2-Bromo-1,3-thiazol-5-yl)methanol is often synthesized via the condensation of thiazole and bromomethyl acetate. The reaction is typically carried out in a suitable solvent such as acetonitrile with a catalytic amount of a base like potassium carbonate. The yield can be increased by optimizing reaction conditions such as temperature and concentration. This compound is often used as a key intermediate in the synthesis of more complex organic molecules.

About

English Name (2-Bromo-1,3-thiazol-5-yl)methanol
Molecular Formula C4H4BrNOS
Molecular Weight 194.05 g/mol
SMILES C1=C(SC(=N1)Br)CO
InChIKey DWNJWSPPORNJGV-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35

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