Compound Q&A
How is 2-Chloroadenosine Hemihydrate (CAS: 81012-94-4) typically synthesized?
Answer
2-Chloroadenosine Hemihydrate is typically synthesized by the chlorination of adenine in the presence of a base. This reaction is catalyzed by Lewis acids, and the product is then crystallized from an aqueous solution. The yield is around 75-80%, and the selectivity for the hemihydrate form is high.
About
CAS No
81012-94-4
English Name
2-Chloroadenosine Hemihydrate
Molecular Formula
C20H26Cl2N10O9
Molecular Weight
621.4 g/mol
SMILES
C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)O)Cl)N.C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)O)Cl)N.O
InChIKey
WRURCFOLSGPTMO-IZGCVNAISA-N
Last Updated: 2025-10-20 00:35
