Compound Q&A
How is 2-Methyl-2-propanyl 4-fluoro-4-(hydroxymethyl)-1-piperidinecarboxylate (CAS: 614730-97-1) typically synthesized?
Answer
2-Methyl-2-propanyl 4-fluoro-4-(hydroxymethyl)-1-piperidinecarboxylate is typically synthesized through a multi-step process involving the protection of a carboxylic acid, followed by a fluoroalkylation reaction. Catalysts such as NaH or other alkali metal hydrides are commonly used. The overall yield is moderate, and the reaction requires precise control of temperature and base concentration to achieve high selectivity and purity. Detailed synthesis protocols and reaction conditions are available in literature and patents.
About
CAS No
614730-97-1
English Name
2-Methyl-2-propanyl 4-fluoro-4-(hydroxymethyl)-1-piperidinecarboxylate
Molecular Formula
C11H20FNO3
Molecular Weight
233.28 g/mol
SMILES
CC(C)(C)OC(=O)N1CCC(CC1)(CO)F
InChIKey
BWZOULIMVKCGII-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
