Compound Q&A
How is 1-Acetyl-5-(2-aminopropyl)-1H-indole-7-carbonitrile (CAS: 175837-01-1) typically synthesized?
Answer
1-Acetyl-5-(2-aminopropyl)-1H-indole-7-carbonitrile is synthesized through a multi-step process involving the reaction of indole with acetyl chloride followed by coupling with an amino propyl derivative. This synthesis typically requires anhydrous conditions and is catalyzed by a suitable reagent. The overall yield is moderate, around 50-70%, with high selectivity towards the desired product due to the specific reactivity of the indole ring.
About
CAS No
175837-01-1
English Name
1-Acetyl-5-(2-aminopropyl)-1H-indole-7-carbonitrile
Molecular Formula
C14H15N3O
Molecular Weight
243.3 g/mol
SMILES
CC(CC1=CC2=C(C(=C1)C#N)N(CC2)C(=O)C)N
InChIKey
DNFHMDAQSKREOD-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
