Compound Q&A
How is N-Trityl Losartan (CAS: 133909-99-6) typically synthesized?
Answer
N-Trityl Losartan (CAS: 133909-99-6) is synthesized through a multi-step process involving the tritylation of the hydroxyl group of losartan. Common catalysts include triphenylphosphine and imidazole. The synthesis yields are typically around 85-90%, and the process involves protecting the functional groups to avoid side reactions.
About
CAS No
133909-99-6
English Name
N-Trityl Losartan
Molecular Formula
C41H37ClN6O
Molecular Weight
665.24 g/mol
SMILES
CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN(N=N4)C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)CO)Cl
InChIKey
QQPGGBNMTNDKEY-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
