Compound Q&A
How is 4-(Trifluoromethyl)-2-pyridinecarboxylic acid (CAS: 588702-62-9) typically synthesized?
Answer
4-(Trifluoromethyl)-2-pyridinecarboxylic acid can be synthesized via a multi-step process involving the coupling of 2-bromopyridine with trifluoromethyl ketone followed by hydrolysis. The synthesis typically requires the use of catalytic amounts of a transition metal catalyst such as palladium and a base like triphenylphosphine. The product is obtained with good yield and selectivity.
About
CAS No
588702-62-9
English Name
4-(Trifluoromethyl)-2-pyridinecarboxylic acid
Molecular Formula
C7H4F3NO2
Molecular Weight
191.11 g/mol
SMILES
C1=CN=C(C=C1C(F)(F)F)C(=O)O
InChIKey
BPRWTROIQXSSOC-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
