Compound Q&A
How is 2-Amino-1,3-thiazole-5-carboxylic acid (CAS: 40283-46-3) typically synthesized?
Answer
2-Amino-1,3-thiazole-5-carboxylic acid can be synthesized by reacting thioacetic acid with hydrazine hydrate, followed by acylation of the hydrazide with an appropriate carboxylic acid chloride. This process involves the formation of a thiazolidine-2,4-dione intermediate, which then cyclizes to the final product. The reaction typically proceeds with good yield and selectivity.
About
CAS No
40283-46-3
English Name
2-Amino-1,3-thiazole-5-carboxylic acid
Molecular Formula
C4H4N2O2S
Molecular Weight
144.16 g/mol
SMILES
C1=C(SC(=N1)N)C(=O)O
InChIKey
ZFMRDDYYJJCBKC-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
