Compound Q&A
How is Isoquinolin-6-ylboronic acid (CAS: 899438-92-7) typically synthesized?
Answer
Isoquinolin-6-ylboronic acid is typically synthesized through the reaction of 6-bromoisoquinoline with borane-dimethyl sulfide complex followed by catalytic hydrogenation. This method provides good yield and selectivity, often using Pd/C as the catalyst. Other routes include direct condensation of appropriate precursors, which can be optimized for specific applications and reactivity profiles.
About
CAS No
899438-92-7
English Name
Isoquinolin-6-ylboronic acid
Molecular Formula
C9H8BNO2
Molecular Weight
172.98 g/mol
SMILES
B(C1=CC2=C(C=C1)C=NC=C2)(O)O
InChIKey
OBUOMTRFSCUDKS-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30
