Compound Q&A

How is 2,2-Dichloro-1-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethanone (CAS: 71526-07-3) typically synthesized?

Answer

2,2-Dichloro-1-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethanone
2,2-Dichloro-1-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethanone (CAS: 71526-07-3) is typically synthesized via the condensation of 1-oxa-4-azaspiro[4.5]dec-4-yl alcohol with chloroacetyl chloride. The reaction proceeds in the presence of a catalytic amount of a base like triethylamine. The product is obtained with good yield and selectivity, and the process is scalable for industrial applications.

About

CAS No 71526-07-3
English Name 2,2-Dichloro-1-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethanone
Molecular Formula C10H15Cl2NO2
Molecular Weight 252.14099999999993 g/mol
SMILES C1CCC2(CC1)N(CCO2)C(=O)C(Cl)Cl
InChIKey QWWHRELOCZEQNZ-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30

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