Compound Q&A

How is (3R,4R)-(-)-1-Benzyl-3,4-pyrrolidindiol (CAS: 163439-82-5) typically synthesized?

Answer

(3R,4R)-(-)-1-Benzyl-3,4-pyrrolidindiol
The compound (3R,4R)-(-)-1-Benzyl-3,4-pyrrolidindiol (CAS: 163439-82-5) can be synthesized via the condensation of benzylamine and 2,3-diaminopyrrolidine. Commonly, this synthesis involves the use of a mild base like triethylamine to promote the reaction. The process typically yields a 70-80% yield with good stereochemical control, ensuring the formation of the (3R,4R) isomer.

About

English Name (3R,4R)-(-)-1-Benzyl-3,4-pyrrolidindiol
Molecular Formula C11H15NO2
Molecular Weight 193.25 g/mol
SMILES C1C(C(CN1CC2=CC=CC=C2)O)O
InChIKey QJRIUWQPJVPYSO-GHMZBOCLSA-N
Last Updated: 2025-10-19 13:36

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