Compound Q&A
How is 5-Nitro-1-isoindolinone (CAS: 876343-38-3) typically synthesized?
Answer
5-Nitro-1-isoindolinone (CAS: 876343-38-3) is typically synthesized via the nitration of 1-isoindolinone using a nitric acid/sulfuric acid mixture. The reaction requires careful control of temperature and concentration to achieve high yield and selectivity. The process can also be catalyzed with iron(III) chloride to improve the reaction rate and selectivity.
About
CAS No
876343-38-3
English Name
5-Nitro-1-isoindolinone
Molecular Formula
C8H6N2O3
Molecular Weight
178.14 g/mol
SMILES
O=C1NCc2c1ccc(c2)[N+](=O)[O-]
InChIKey
CZXUANYPXDFFOG-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36
