Compound Q&A
How is tert-Butyl 3-(2-aminoethyl)azetidine-1-carboxylate (CAS: 898271-20-0) typically synthesized?
Answer
tert-Butyl 3-(2-aminoethyl)azetidine-1-carboxylate is typically synthesized through a multi-step process involving the reaction of tert-butyl azetidine-1-carboxylate with chloroacetylene, followed by nucleophilic substitution to form the aminoethyl derivative. Commonly used catalysts include sodium hydride, and the reaction is performed in an inert atmosphere to prevent side reactions. The overall yield is around 80-85%.
About
CAS No
898271-20-0
English Name
tert-Butyl 3-(2-aminoethyl)azetidine-1-carboxylate
Molecular Formula
C10H20N2O2
Molecular Weight
200.28 g/mol
SMILES
CC(C)(C)OC(=O)N1CC(C1)CCN
InChIKey
XQNQFOKZUQWWDO-UHFFFAOYSA-N
Last Updated: 2025-10-19 13:36
