Compound Q&A
How is Dolasetron Mesylate (CAS: 115956-13-3) typically synthesized?
Answer
Dolasetron Mesylate (CAS: 115956-13-3) is typically synthesized by the methylation of dolasetron hydrochloride. The process involves the reaction of dolasetron hydrochloride with methylsulfonyl chloride in the presence of a base, such as triethylamine, followed by the addition of methylsulfonic acid. The resulting product is dolasetron mesylate, which is then purified through recrystallization from an appropriate solvent.
About
CAS No
115956-13-3
English Name
Dolasetron Mesylate
Molecular Formula
C20H26N2O7S
Molecular Weight
438.5 g/mol
SMILES
CS(=O)(=O)O.C1C2CC3CC(CC1N3CC2=O)OC(=O)C4=CNC5=CC=CC=C54.O
InChIKey
QTFFGPOXNNGTGZ-RCSCTSIBSA-N
Last Updated: 2025-10-19 13:36