Compound Q&A

How is 4-Bromo-1-chloroisoquinoline (CAS: 66728-98-1) typically synthesized?

Answer

4-Bromo-1-chloroisoquinoline
4-Bromo-1-chloroisoquinoline (CAS: 66728-98-1) is typically synthesized via a multi-step process involving the bromination of 1-chloroisatin followed by a condensation reaction. The reaction is catalyzed by phosphorus oxychloride and proceeds with high selectivity, yielding a high percentage of the desired product. The process involves careful control of reaction conditions to ensure purity and yield.

About

CAS No 66728-98-1
English Name 4-Bromo-1-chloroisoquinoline
Molecular Formula C9H5BrClN
Molecular Weight 242.503 g/mol
SMILES C1=CC=C2C(=C1)C(=CN=C2Cl)Br
InChIKey HRWILRGBDZGABZ-UHFFFAOYSA-N
Last Updated: 2025-10-17 07:35

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