Compound Q&A
How is 7-Chloro-1H-pyrrolo[3,2-b]pyridine (CAS: 357263-48-0) typically synthesized?
Answer
![7-Chloro-1H-pyrrolo[3,2-b]pyridine](https://static.chemtradehub.com/structs/357/357263-48-0-fb45.webp "7-Chloro-1H-pyrrolo[3,2-b]pyridine")
7-Chloro-1H-pyrrolo[3,2-b]pyridine is synthesized via a multi-step procedure involving the chlorination of 1H-pyrrolo[3,2-b]pyridine. The reaction is typically carried out using thionyl chloride in an inert solvent like toluene. The yield is around 85%, and the method involves careful temperature control to achieve high selectivity and purity.
About
CAS No
357263-48-0
English Name
7-Chloro-1H-pyrrolo[3,2-b]pyridine
Molecular Formula
C7H5ClN2
Molecular Weight
152.58 g/mol
SMILES
C1=CNC2=C(C=CN=C21)Cl
InChIKey
ZBEYLQBHTDNDDR-UHFFFAOYSA-N
Last Updated: 2025-10-17 07:35
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