Compound Q&A
How is 2,4-Dichloro-6-fluoroquinazoline (CAS: 134517-57-0) typically synthesized?
Answer
2,4-Dichloro-6-fluoroquinazoline is synthesized via a multi-step process starting from 2,4-dichloroquinazoline. The key steps involve fluorination of the nitrogen and subsequent chlorination, typically using reagents like hydrogen fluoride and thionyl chloride. The overall yield is around 70-80% with good selectivity.
About
CAS No
134517-57-0
English Name
2,4-Dichloro-6-fluoroquinazoline
Molecular Formula
C8H3Cl2FN2
Molecular Weight
217.03 g/mol
SMILES
C1=CC2=C(C=C1F)C(=NC(=N2)Cl)Cl
InChIKey
VLPYLGGGYDUVJN-UHFFFAOYSA-N
Last Updated: 2025-10-17 07:35
