Compound Q&A
How is 1-Cbz-azetidine-3-carboxylic acid (CAS: 97628-92-7) typically synthesized?
Answer
1-Cbz-azetidine-3-carboxylic acid is often synthesized through amidification of 1-Cbz-azetidine-3-carboxylic anhydride with appropriate bases. The reaction typically proceeds with good yield and selectivity using stoichiometric amounts of base under reflux conditions. Common catalysts include triethylamine and pyridine.
About
CAS No
97628-92-7
English Name
1-Cbz-azetidine-3-carboxylic acid
Molecular Formula
C12H13NO4
Molecular Weight
235.24 g/mol
SMILES
C1C(CN1C(=O)OCC2=CC=CC=C2)C(=O)O
InChIKey
PVJPBKZGIUAESY-UHFFFAOYSA-N
Last Updated: 2025-10-17 07:35
