Compound Q&A
How is Ethyl 4,6-dichloro-2-methylnicotinate (CAS: 686279-09-4) typically synthesized?
Answer
Ethyl 4,6-dichloro-2-methylnicotinate is typically synthesized via the condensation of 4,6-dichloro-2-methylpyridine with acetyl chloride in the presence of anhydrous aluminum chloride as a catalyst. The reaction yields a mixture of isomers, but the desired one can be isolated through recrystallization. The reaction is exothermic and requires careful temperature control.
About
CAS No
686279-09-4
English Name
Ethyl 4,6-dichloro-2-methylnicotinate
Molecular Formula
C9H9Cl2NO2
Molecular Weight
234.08 g/mol
SMILES
CCOC(=O)C1=C(N=C(C=C1Cl)Cl)C
InChIKey
LNIMLSAAPISOEC-UHFFFAOYSA-N
Last Updated: 2025-10-17 07:35
