Compound Q&A

How is (3Z)-3-(Acetoxyimino)-5-chloro-1-(2,5-dichlorobenzyl)-1,3-dihydro-2H-indol-2-one (CAS: 668467-91-2) typically synthesized?

Answer

(3Z)-3-(Acetoxyimino)-5-chloro-1-(2,5-dichlorobenzyl)-1,3-dihydro-2H-indol-2-one
The compound is typically synthesized via a multi-step reaction involving acetoxyimino dehydratase, followed by acylation and chlorination. Common catalysts include Lewis acids like aluminum chloride. The yield is generally around 70-80%, and the reaction is carried out under anhydrous conditions to avoid side reactions.

About

English Name (3Z)-3-(Acetoxyimino)-5-chloro-1-(2,5-dichlorobenzyl)-1,3-dihydro-2H-indol-2-one
Molecular Formula C17H11Cl3N2O3
Molecular Weight 397.65 g/mol
SMILES CC(=O)ON=C1C2=C(C=CC(=C2)Cl)N(C1=O)CC3=C(C=CC(=C3)Cl)Cl
InChIKey OPQRFPHLZZPCCH-PGMHBOJBSA-N
Last Updated: 2025-10-16 16:48

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