Compound Q&A

How is (2R)-2-Ammonio-3-(1,3-thiazol-4-yl)propanoate (CAS: 131896-42-9) typically synthesized?

Answer

(2R)-2-Ammonio-3-(1,3-thiazol-4-yl)propanoate
(2R)-2-Ammonio-3-(1,3-thiazol-4-yl)propanoate can be synthesized through a multi-step process involving the reaction of thioacetamide with ammonia and subsequent modification to form the thiazole ring. Common methods include the use of potassium hydroxide as a catalyst and ethyl acetate as the solvent. The yield is usually high, and the product is purified by recrystallization from water.

About

English Name (2R)-2-Ammonio-3-(1,3-thiazol-4-yl)propanoate
Molecular Formula C6H8N2O2S
Molecular Weight 172.21 g/mol
SMILES C1=C(N=CS1)CC(C(=O)O)N
InChIKey WBZIGVCQRXJYQD-RXMQYKEDSA-N
Last Updated: 2025-10-16 16:48

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