Compound Q&A
How is m-PEG4-NHS ester (CAS: 622405-78-1) typically synthesized?
Answer
m-PEG4-NHS ester (CAS: 622405-78-1) is synthesized by reacting polyethylene glycol (PEG) with N-hydroxysuccinimide (NHS) ester. The reaction is typically catalyzed by a carbodiimide such as EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide). The reaction yields a high degree of selectivity and provides a clean product with high yield. The process is often carried out in a solvent such as DCM (dichloromethane) or DMF (dimethylformamide).
About
CAS No
622405-78-1
English Name
m-PEG4-NHS ester
Molecular Formula
C14H23NO8
Molecular Weight
333.34 g/mol
SMILES
COCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
InChIKey
MAYFFZZPEREGBQ-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48
