Compound Q&A
How is 2-Bromo-4'-chloro-1,1'-biphenyl (CAS: 179526-95-5) typically synthesized?
Answer
2-Bromo-4'-chloro-1,1'-biphenyl is commonly synthesized via bromination of 4'-chlorophenylphenyl ether using N-bromosuccinimide (NBS) in the presence of a radical initiator. The reaction yields a mixture that requires purification by recrystallization. Other methods include direct coupling reactions under photoreduction or palladium-catalyzed cross-coupling conditions.
About
CAS No
179526-95-5
English Name
2-Bromo-4'-chloro-1,1'-biphenyl
Molecular Formula
C12H8BrCl
Molecular Weight
267.553 g/mol
SMILES
C1=CC=C(C(=C1)C2=CC=C(C=C2)Cl)Br
InChIKey
WSHZWUXRWQVZQP-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48
