How is (1s,3s,5s)-1,3,5-Adamantanetriol (CAS: 99181-50-7) typically synthesized?

(1s,3s,5s)-1,3,5-Adamantanetriol can be synthesized through the condensation of 3,5-dihydroxy-1-cyclohexene with dihydroxybenzene under basic conditions. Common catalysts include sodium hydroxide or potassium hydroxide. The reaction typically yields high selectivity and good yield. Distillation and recrystallization are used to purify the product. This method allows for the production of the compound in a controlled and efficient manner.