Compound Q&A

How is 2,3,4-trifluoro-5-nitrobenzoic acid (CAS: 197520-71-1) typically synthesized?

Answer

2,3,4-trifluoro-5-nitrobenzoic acid
2,3,4-Trifluoro-5-nitrobenzoic acid can be synthesized by the nitration of 2,3,4-trifluorobenzoic acid using concentrated nitric acid and sulfuric acid as a catalyst. The reaction is performed under nitration conditions, ensuring high selectivity and yield. Post-nitration, the product is isolated and purified through recrystallization.

About

English Name 2,3,4-trifluoro-5-nitrobenzoic acid
Molecular Formula C7H2F3NO4
Molecular Weight 221.09 g/mol
SMILES C1=C(C(=C(C(=C1[N+](=O)[O-])F)F)F)C(=O)O
InChIKey BCMIOBTWFPSPJJ-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48

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