Compound Q&A
How is 2-Chloro-5-(trifluoromethyl)-3-pyridinamine (CAS: 72587-18-9) typically synthesized?
Answer
2-Chloro-5-(trifluoromethyl)-3-pyridinamine is typically synthesized via a nucleophilic substitution reaction involving 5-chloro-3-pyridinamine and trifluoromethyl chloromethyl ether. The reaction is catalyzed by a Lewis acid such as aluminum chloride and proceeds with good selectivity and yield under anhydrous conditions.
About
CAS No
72587-18-9
English Name
2-Chloro-5-(trifluoromethyl)-3-pyridinamine
Molecular Formula
C6H4ClF3N2
Molecular Weight
196.56 g/mol
SMILES
C1=C(C=NC(=C1N)Cl)C(F)(F)F
InChIKey
HABKYPVMMHBOIW-UHFFFAOYSA-N
Last Updated: 2025-10-13 19:39
