Compound Q&A

How is 2-Chloro-4,6-dimethylnicotinonitrile (CAS: 14237-71-9) typically synthesized?

Answer

2-Chloro-4,6-dimethylnicotinonitrile
2-Chloro-4,6-dimethylnicotinonitrile (CAS: 14237-71-9) can be synthesized by reacting 2,6-dimethylpyridine with chloroacetonitrile and a base. Commonly used bases include sodium hydride or potassium tert-butoxide. The reaction is typically carried out in anhydrous conditions to enhance selectivity and yield.

About

CAS No 14237-71-9
English Name 2-Chloro-4,6-dimethylnicotinonitrile
Molecular Formula C8H7ClN2
Molecular Weight 166.61 g/mol
SMILES CC1=CC(=NC(=C1C#N)Cl)C
InChIKey RETJKTAVEQPNMH-UHFFFAOYSA-N
Last Updated: 2025-10-13 15:08

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