Compound Q&A
How is 5-Bromo-2,4-bis[(2-methyl-2-propanyl)oxy]pyrimidine (CAS: 19752-61-5) typically synthesized?
Answer
![5-Bromo-2,4-bis[(2-methyl-2-propanyl)oxy]pyrimidine](https://static.chemtradehub.com/structs/197/19752-61-5-5dc1.webp "5-Bromo-2,4-bis[(2-methyl-2-propanyl)oxy]pyrimidine")
5-Bromo-2,4-bis[(2-methyl-2-propanyl)oxy]pyrimidine is typically synthesized via the bromination of 2,4-bis[(2-methyl-2-propanyl)oxy]pyrimidine using a brominating agent like N-bromosuccinimide (NBS) and a suitable solvent such as acetonitrile. The reaction is monitored by TLC (thin-layer chromatography) and typically achieves a yield of around 70-80%. The use of a catalyst like azobisisobutyronitrile (AIBN) can enhance the selectivity and yield of the product.
About
CAS No
19752-61-5
English Name
5-Bromo-2,4-bis[(2-methyl-2-propanyl)oxy]pyrimidine
Molecular Formula
C12H19BrN2O2
Molecular Weight
303.2 g/mol
SMILES
CC(C)(C)OC1=NC(=NC=C1Br)OC(C)(C)C
InChIKey
MAWUVEDTRZARNC-UHFFFAOYSA-N
Last Updated: 2025-10-13 12:55
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