Compound Q&A

How is N6-Benzoyl-2'-o-methyl-adenosine (CAS: 85079-00-1) typically synthesized?

Answer

N6-Benzoyl-2'-o-methyl-adenosine
N6-Benzoyl-2'-o-methyl-adenosine is typically synthesized by the benzoylation of 2'-o-methyl-adenosine via a nucleophilic substitution reaction, followed by derivatization. Common reagents include benzoyl chloride and a suitable base such as triethylamine. The yield is usually around 85%, and the reaction is performed under anhydrous conditions to avoid side reactions.

About

CAS No 85079-00-1
English Name N6-Benzoyl-2'-o-methyl-adenosine
Molecular Formula C18H19N5O5
Molecular Weight 385.38 g/mol
SMILES OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN=C3NC(C4=CC=CC=C4)=O)O1)OC)O
InChIKey PHFHSPQCDRKMQJ-XWXWGSFUSA-N
Last Updated: 2025-10-10 19:08

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