Compound Q&A
How is (4-Chlorophenyl)(hydroxy)acetic acid (CAS: 492-86-4) typically synthesized?
Answer
(4-Chlorophenyl)(hydroxy)acetic acid is typically synthesized through the reaction of 4-chlorophenol with acetic anhydride in the presence of a catalyst such as pyridine. The reaction involves acetylation of the phenolic hydroxyl group, followed by deprotonation and re-protonation to form the desired compound. The yield is generally around 80-85%, and the method is scalable for industrial production.
About
CAS No
492-86-4
English Name
(4-Chlorophenyl)(hydroxy)acetic acid
Molecular Formula
C8H7ClO3
Molecular Weight
186.59 g/mol
SMILES
C1=CC(=CC=C1C(C(=O)O)O)Cl
InChIKey
BWSFWXSSALIZAU-UHFFFAOYSA-N
Last Updated: 2025-10-07 19:42
