Compound Q&A
How is Daclatasvir dihydrochloride (CAS: 1009119-65-6) typically synthesized?
Answer
Daclatasvir dihydrochloride is synthesized through a multi-step process involving condensation reactions, amidation, and hydrochloridation steps. The key reaction involves the coupling of a protected amino acid derivative with an aromatic ring, followed by deprotection and hydrochloridation. The process yields a highly selective and pure product with good yield.
About
CAS No
1009119-65-6
English Name
Daclatasvir dihydrochloride
Molecular Formula
C40H52Cl2N8O6
Molecular Weight
811.812 g/mol
SMILES
COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc([nH]1)c1ccc(cc1)c1ccc(cc1)c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@H](C(C)C)NC(=O)OC)C(C)C.Cl.Cl
InChIKey
BVZLLUDATICXCI-JMSCDMLISA-N
Last Updated: 2025-10-07 19:42
